Targeting Metastasis – Understanding Cell Plasticity and the Tumour Niche

Metastasis is responsible for over 90% of cancer-related deaths. In order for cancer cells to spread, they need to adapt to the environment they encounter. Their research aims to understand how cancer cells navigate cancer remodeled extracellular matrix (ECM) and how changes in ECM composition and topology can drive tumorigenesis. Their work is multidisciplinary and takes advantage of various imaging modalities to understand cancer cell migration and ECM remodeling in vivo and ex vivo.

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